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. 2017 Feb 15;66(5):1380–1390. doi: 10.2337/db16-1181

Figure 2.

Figure 2

Blood glucose values after implantation of an insulin pellet (A) or after a single subcutaneous injection of 4 IU insulin (B) in otherwise untreated STZ diabetic rats. Data are group mean ± SEM of N = 6/group. *P < 0.05, **P < 0.01, ***P < 0.001 compared with time 0 by repeated-measures ANOVA followed by the Dunnett post hoc test. C: RDD measured in these two groups of diabetic rats and in untreated diabetic rats (untreated) 4 days after initiation of insulin therapy and 12 h after the last insulin injection. Data are group mean ± SEM of N = 6/group. *P < 0.05 vs. untreated diabetic rats by one-way ANOVA followed by the Dunnett post hoc test.