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. 2017 Mar 1;66(5):1237–1246. doi: 10.2337/db16-1057

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© 2017 by the American Diabetes Association.

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Seasonal changes in UCP1 and TMEM26 immunohistochemistry in thigh SC WAT. A: Histochemical analysis of UCP1 expression in thigh SC WAT of two lean subjects in the summer and winter. The left panel shows no primary antibody control. The arrows in the middle panels point to UCP1 staining in unilocular adipocytes in the summer. The arrows in the right panels point to UCP1 staining in cells between adipocytes in the winter. B: TMEM26 staining in the same subjects. The arrow points to TMEM26 staining in cells between adipocytes in the winter. Scale bars = 50 μm.