Fig. 3.
set-4 acts in the nervous system to promote dauer arrest. (A) Representative photomicrographs showing colocalization of GFP and mCherry in animals co-expressing set-4p::gfp and the pan-neuronal reporter rab-3p::mcherry (n=15). (B) Representative photomicrographs showing colocalization of red and green fluorescence in amphid neurons of set-4p::gfp transgenic animals exposed to DiI (n=21). (C) Rescue of dauer arrest in set-4;eak-7;akt-1 mutants by set-4 transgenes driven by native set-4 or tissue-specific promoters (n=2328, 2143, 2058, 662, 811, 705, 936, 516, 541).