Table 2.
Treatment exposure (FAS)
| PHN (n = 89) |
HIV-AN (n = 5) |
NBP (n = 50) |
CRNP (n = 22) |
PONP (n = 198) |
Other (n = 56) |
Overall (n = 420) |
|
|---|---|---|---|---|---|---|---|
| Patients treated at each application, n (%) | |||||||
| First treatment | 89 (21.2) | 5 (1.2) | 50 (11.9) | 22 (5.2) | 198 (47.1) | 56 (13.3) | 420 (100) |
| Second treatment | 40 (9.5) | 2 (0.5) | 15 (3.6) | 8 (1.9) | 97 (23.1) | 19 (4.5) | 181 (43.1) |
| Third treatment | 16 (3.8) | – | 4 (1.0) | 4 (1.0) | 38 (9.0) | 8 (1.9) | 70 (16.7) |
| Mean size of treatment area, cm2 (SD) | |||||||
| First treatment | 298.6 (168.1) | 380.0 (138.6) | 297.7 (196.9) | 519.5 (404.9) | 271.5 (209.7) | 362.0 (263.9) | 306.4 (228.2) |
| Second treatment | 286.8 (169.3) | 210.0 (99.0) | 291.3 (160.6) | 566.6 (387.9) | 278.6 (206.4) | 391.5 (300.5) | 306.4 (225.0) |
| Third treatment | 270.0 (190.6) | – | 357.5 (230.7) | 467.5 (113.5) | 229.7 (211.8) | 487.4 (412.4) | 294.8 (248.8) |
| Mean number of patches (SD) | |||||||
| First treatment | 1.4 (0.6) | 1.4 (0.6) | 1.3 (0.6) | 2.1 (1.3) | 1.4 (0.7) | 1.6 (0.8) | 1.5 (0.7) |
| Second treatment | 1.4 (0.6) | 1.0 (0.0) | 1.4 (0.6) | 2.3 (1.2) | 1.5 (0.7) | 1.7 (0.9) | 1.5 (0.7) |
| Third treatment | 1.4 (0.7) | – | 1.8 (1.0) | 2.0 (0.0) | 1.4 (0.8) | 2.0 (1.3) | 1.6 (0.8) |
| Patients completing ≥90% of recommended treatment durationa, n (%) | |||||||
| First treatment | 84 (94.4) | 5 (100) | 47 (94.0) | 19 (86.4) | 184 (93.9) | 49 (87.5) | 388 (92.8) |
| Second treatment | 37 (94.9) | 2 (100) | 12 (85.7) | 7 (87.5) | 81 (94.2) | 18 (100) | 157 (94.0) |
| Third treatment | 16 (100) | – | 4 (100) | 4 (100) | 33 (100) | 7 (87.5) | 63 (98.4) |
aRecommended treatment duration times were 30 min for foot and 60 min for other anatomical locations. For patients treated on the foot, the treatment time corresponding to the percentage duration was 27–33 min for ≥90% to <110% and >33 min for ≥110%. For patients treated on other locations, the treatment time corresponding to the percentage duration was 54–66 min for ≥90% to <110% and >66 min for ≥110%. CRNP, cancer-related neuropathic pain; FAS, full analysis set; HIV-AN, HIV associated neuropathy; NPRS, numeric pain rating scale; PHN, postherpetic neuralgia; NBP, neuropathic back pain; Other, other non-diabetic PNP; PONP, post-operative and post-traumatic neuropathic pain; SD, standard deviation