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Quantification of tracheal epithelial cells with abnormal mitochondria
| Basal cells | Club cells | Ciliated cells | |
|---|---|---|---|
| WT | 17% (n = 30) | 14% (n = 66) | 0% (n = 63) |
| WT (aged) | 24% (n = 34) | 11% (n = 61) | 0% (n = 50) |
| Aldh2*2 Tg | 19% (n = 31) | 13% (n = 61) | 0% (n = 53) |
| Aldh2 −/− | 88% (n = 41) | 96% (n = 75) | 14% (n = 65) |
Percentage of cells with more than 80% of its mitochondria abnormal within a cell type
(n = Number of cells examined per group)
