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Growth kinetics of the WA and AW hemagglutinin single mutants (filled squares and dashed line, open squares and solid line, respectively) compared to those of a virus bearing the full parental (WW) or a double mutant (AA) hemagglutinin. Viral titres are expressed as log(viral copies/µl supernatant). Mean yield±SD from four replicate infections is shown for each virus at each time point.
