Table 3.
Prior and Posterior Estimates of Risk Factors for Reinfection With Hepatitis C in Patients With a Sustained Virologic Response After Treatment
| Risk Factor | Prior HR (95% CrI) | Posterior HR (95% CrI) |
|---|---|---|
| MSM (vs heterosexual male) a | 1.5 (0.38–6.0) | 1.7 (0.62–3.4) |
| High-risk sexual behavior in MSM a,b | 1.5 (0.38–6.0) | 1.8 (0.56–4.4) |
| Low frequency IDU a,c | 1.5 (0.38–6.0) | 2.3 (0.53–6.3) |
| High frequency IDU a,d | 2.0 (0.50–8.0) | 6.1 (2.5–12) |
| Shared IDU equipment a,e | 2.0 (0.50–8.0) | 2.0 (0.44–5.6) |
| Female (vs heterosexual male) | 1.0 (0.25–4.0) | 1.0 (0.32–2.5) |
| Aboriginal ethnicity | 1.0 (0.25–4.0) | 1.6 (0.42–4.1) |
| Age at sustained virologic response (per 10-year increase) | 0.67 (0.17–2.7) | 0.90 (0.48–1.5) |
| Latest CD4+ cell count (per 100 cells/μL increase) | 0.67 (0.17–2.7) | 0.82 (0.62–1.0) |
Canadian Co-infection Cohort, n = 257.
Abbreviations: CrI, credible interval; HR, hazard ratio; IDU, injection drug use; MSM, men who have sex with men.
aPatient report of behavior in the previous 6 months.
bPatient reports more than 1 male sexual partner and less-than-perfect condom use.
cPatient reports injecting drugs other than cocaine or methamphetamines (mainly opiates).
dPatient reports injecting cocaine or methamphetamines.
ePatient reports shared use of needles or of other paraphernalia, such as containers and spoons.