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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2017 Mar;10(3):e004667. doi: 10.1161/CIRCEP.116.004667

Figure 6.

Figure 6

A. Schematic illustrating how APD shortening due to ATP-sensitive K+ current (IKATP) activation offsets net cellular K+ loss by decreasing the average driving force Em-EK for K+ efflux over the cardiac cycle. B. ADP shortening, conduction time (CT) delay, tension development and interstitial [K+]o accumulation versus time during acute global ischemia in rabbit ventricle. Reproduced from Weiss & Shine 48 with permission.