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. 2017 Apr 21;12(4):e0176039. doi: 10.1371/journal.pone.0176039

Table 2. Association of tertiles of biomarker of soy intake (24UI) with cardiovascular risks, fasting blood, and 24U in Japanese, Hyogo inhabitants aged 30 to 79 Years.

Tertile of 24UI/Creatinine ratio, mmol/mmol P for linear trend1
1 (low) 2 3 (high)
Median 0.3 1.1 3.6
Range 0.0–0.6 0.6–1.9 2.0–15.6
Body mass Index
 n 100 102 101
 Crude 22.4 ± 0.32 22.8 ± 0.3 22.2 ± 0.3 NS
 Age and gender adjusted 22.4 ± 0.3 22.8 ± 0.3 22.2 ± 0.3 NS
Systolic blood pressure (mmHg)
 n 100 102 101
 Crude 121.9 ± 1.6 122.1 ± 1.8 123.9 ± 1.6 NS
 Age and gender adjusted 123.2 ± 1.6 122.6 ± 1.5 121.9 ± 1.6 NS
Diastolic blood pressure (mmHg)
 n 100 102 101
 Crude 73.5 ± 1.2 73.9 ± 1.2 72.4 ± 1.1 NS
 Age and gender adjusted 73.1 ± 1.2 74.1 ± 1.1 72.6 ± 1.2 NS
Serum total cholesterol (mg/dL)
 n 100 102 101
 Crude 202.7 ± 3.4 201.5 ± 3.4 216.0 ± 3.6 p<0.01
 Age and gender adjusted 208.5 ± 3.4 202.5 ± 3.3 209.2 ± 3.4 NS
Low-density lipoprotein cholesterol (mg/dL)
 n 100 102 101
 Crude 120.6 ± 3.2 119.6 ± 3.1 129.3 ± 3.3 p<0.05
 Age and gender adjusted 125.7 ± 3.1 120.6 ± 3.0 123.2 ± 3.1 NS
High-density lipoprotein cholesterol (mg/dL)
 n 100 102 101
 Crude 61.9 ± 1.4 62.2 ± 1.6 65.0 ± 1.4 NS
 Age and gender adjusted 62.4 ± 1.5 62.0 ± 1.4 64.8 ± 1.5 NS
Triglyceride (mg/dL)
 n 95 100 97
 Crude 104.2 ± 6.8 105.2 ± 7.3 108.3 ± 7.4 NS
 Age and gender adjusted 102.9 ± 7.3 106.0 ± 6.9 108.7 ± 7.4 NS
Folate (ng/mL)
 n 100 102 101
 Crude 5.8 ± 0.3 6.4 ± 0.3 8.4 ± 0.4 p<0.01
 Age and gender adjusted 6.0 ± 0.3 6.4 ± 0.3 8.1 ± 0.3 p<0.01
24U Salt (g/day)
 n 100 102 101
 Crude 10.5 ± 0.4 11.5 ± 0.4 11.6 ± 0.5 NS
 Age and gender adjusted 9.9 ± 0.5 11.4 ± 0.4 12.3 ± 0.5 p<0.001
24U potassium (g/day)
 n 100 102 101
 Crude 1.7 ± 0.1 1.9 ± 0.1 2.4 ± 0.1 p<0.001
 Age and gender adjusted 1.7 ± 0.1 1.9 ± 0.1 2.3 ± 0.1 p<0.001
Sodium/potassium ratio (mEq/mEq)
 n 100 102 101
 Crude 4.5 ± 0.2 4.3 ± 0.2 3.5 ± 0.2 p<0.001
 Age and gender adjusted 4.2 ± 0.2 4.2 ± 0.2 3.8 ± 0.2 NS

Abbreviations: n, number; 24U, 24-hour urine; 24UI, 24-hour urinary isoflavones.

1 From multiple linear regression models for the relationship between 24UI/creatinine ratio and cardiovascular risks, fasting blood, and 24U.

2Mean ± standard error (SE) (all such values).