Table 1. Smear sensitivity, Xpert sensitivity and specificity, added value (Δ%) of Xpert compared to smear microscopy in MTB culture-positive samples.

	Sample, n	MTB culture-positive, n	Smear Sensitivity, % (95% CI)	Xpert Sensitivity, % (95% CI)	Δ Xpert vs Smear, % (95% CI)	Xpert Specificity, % (95% CI)
Total	5027	386	39.4 (34.5–44.5)	83.7 (79.6–87.2)	44.3 (39.4–49.2)	99.1 (98.7–99.3)
By sample type
Respiratory	3067	274	50.0 (43.9–56.1)	86.5 (81.9–90.3)	36.5 (30.8–42.2)	99.0 (98.6–99.4)
Non- respiratory	1960	112	13.4 (7.7–21.1)	76.8 (67.9–84.2)	63.4 (54.5–72.3)	99.1 (98.5–99.5)
By assay version
G3	863	84		84.5 (75.0–91.5)		98.8 (97.8–99.5)
G4	4164	302		83.4 (78.8–87.5)		99.1 (98.7–99.4)
In smear-negative
Total	4860	234		73.1 (66.9–78.7)		99.1 (98.8–99.3)
Respiratory	2917	137		73.0 (64.8–80.2)		99.0 (98.6–99.4)
Non-respiratory	1943	97		73.2 (63.2–81.7)		99.1 (98.6–99.5)