Figure 2.

Statistical analysis of gene expression experiment results for a liver cancer versus normal cell line. Users can upload a list of genes/transcripts, along with an associated value (e.g. fold change, but can be any continuous variable). The list is divided automatically into groups sharing the same function (molecular function, biological process or pathway), and the distribution of values for each group is compared statistically with the overall distribution using the Mann–Whitney U-test to look for coordinated changes across each group (10).