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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Nutr Intermed Metab. 2017 Mar 8;8:1–7. doi: 10.1016/j.jnim.2017.03.002

Figure 1.

Figure 1

Manhattan plot of epigenome-wide results of testing for association between methylation at > 450,000 cytosine-phosphate-guanine sites and circulating trimethylamine-N-oxide. The X-axis displays the chromosome on which the site is located, the Y-axes display −log10(P-value). The red horizontal line indicates the threshold for epigenome-wide statistical significance after a Bonferroni correction. [Format double column; color figure]