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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Nutr Intermed Metab. 2017 Mar 8;8:1–7. doi: 10.1016/j.jnim.2017.03.002

Table 2.

Top epigenome-wide associations for circulating TMAO in GOLDN (n=847).*

Marker Chromosome Region Gene β ± SE P-value
cg08040395 17 – ENGASE 0.01±0.002 2.2×10−6
cg19731194 1 – Intergenic 0.01±0.002 8.8×10−6
cg21066735 11 Island Intergenic 0.002±0.0004 1.3×10−5
cg00089486 3 South Shore SHOX2 0.003±0.0007 1.6×10−5
cg01515960 19 Island Intergenic 0.01±0.003 1.6×10−5
cg25778892 7 North Shore Intergenic 0.01±0.002 2.0×10−5
cg27427369 2 South Shelf ERLEC1; LOC10030265 −0.003±0.0006 2.8×10−5
cg01767862 14 – SNORD114-28 −0.003±0.0008 3.6×10−5
cg00810908 3 Island FBLN2 0.002±0.0004 3.7×10−5
cg08055924 4 Island MIR574; FAM114A1 0.003±0.0008 4.4×10−5
*

TMAO, trimethylamine-N-oxide