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Changes of EPAS1 expression in Tibetan umbilical endothelial cells during prolonged hypoxic treatment (A) and in term Tibetan placentas (B). The adaptive ECU lines are homozygotes of the adaptive EPAS1 haplotype, and the wildtype ECU lines are homozygotes of the wildtype EPAS1 haplotype. TIB Hom, Tibetan homozygote; TIB Het, Tibetan heterozygote; Han Hom, Han Chinese homozygote; WT, wild-type. The one-way ANOVA and two-tailed t tests were conducted for panel A and panel B, respectively.
