Table 1. Comparative table of percentage change in various A) metabolic and B) mitochondrial alterations in human and mouse tissues.
| A. | ||||
|---|---|---|---|---|
| Hif1-alpha | GLUT1 | PKM2 | LDHA | |
| Patients w/ Adenoma(s) vs Control Patients | 53% increase | ∼46% increase | ∼35% increase | 38% increase |
| AOM Rat vs Saline Rat | ∼55% increase | 29% increase | 74% increase | 60% increase |
| Pirc Rat vs Wildtype Rat | 50% increase | 35% increase | 33% increase | 40% increase |
| B. | |||||
|---|---|---|---|---|---|
| mtND1 | DRP1 | OPA-1 | PGC1-α | UCP2 | |
| Patients w/ Adenoma(s) vs Control Patients | 76% increase | ∼33% increase | 52% increase | ∼26% increase | 78% increase |
| AOM Rat vs Saline Rat | 100% increase | 15% increase | ∼67% increase | 11% decrease | 75% increase |
| Pirc Rat vs Wildtype Rat | 50% increase | 45% increase | 61% increase | ∼66% increase | 100% increase |