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. 2017 Feb 16;8(13):20667–20678. doi: 10.18632/oncotarget.15400

Figure 9. Treatment with CAPE lowers mitochondrial respiration.

Figure 9

The metabolic OCR profile of MCF7 cells grown in monolayers, after 72 hours of treatment with CAPE, was examined using the Seahorse XFe96 analyser (Top panel, representative experiment). The bar graph, in the Lower panel, shows that the all the parameters relative to the oxygen consumption (OCR), are significantly decreased by both concentration of CAPE, 10 μM and 25 μM, as compared to the vehicle-treated control cells (DMSO). The bar graph shows the mean ± SEM, t-test, two-tailed test. **p < 0.005, ***p < 0.0001. N = 3 independent experiments.