Table 3. Summary of the subgroup analyses in this meta-analysis.

Comparison	Category	Category	Studies	OR (95% CI)	P-value
rs6920220
A vs. G	Ethnicity	Caucasian	10	1.19(1.11,1.28)	< 0.001
		Tunisian	1	1.20(0.84,1.72)	0.326
		African–American	1	0.90(0.70,1.16)	0.412
		Asian	2	0.69(0.08,5.89)	0.733
	HWE status	negative	3	1.22(1.14,1.30)	< 0.001
		positive	11	1.16(1.05,1.28)	0.004
GA+AA vs. GG	Ethnicity	Caucasian	10	1.21(1.12,1.31)	< 0.001
		Tunisian	1	1.29(0.83,2.00)	0.264
		African–American	1	0.89(0.68,1.17)	0.419
		Asian	2	0.69(0.08,5.92)	0.733
	HWE status	negative	3	1.24(1.15,1.33)	< 0.001
		positive	11	1.18(1.05,1.32)	0.005
AA vs. GA+GG	Ethnicity	Caucasian	10	1.37(1.24,1.51)	< 0.001
		Tunisian	1	1.09(0.42,2.83)	0.862
		African–American	1	0.85(0.31,2.36)	0.758
	HWE status	negative	3	1.49(1.25,1.78)	< 0.001
		positive	9	1.31(1.17,1.47)	< 0.001
rs2230926
G vs. T	Ethnicity	Asian	4	1.42(1.21,1.67)	< 0.001
		African–American	1	0.96(0.81,1.14)	0.627
		Caucasian	1	2.00(1.16,3.46)	0.013
	HWE status	negative	1	2.40(1.34,4.30)	0.003
		positive	5	1.29(1.04,1.60)	0.020
TG+GG vs. TT	Ethnicity	Asian	4	1.45(1.21,1.74)	< 0.001
		African–American	1	0.95(0.75,1.21)	0.678
		Caucasian	1	1.94(1.09,3.46)	0.024
	HWE status	negative	1	2.67(1.41,5.04)	0.002
		positive	5	1.30(1.07,1.59)	0.010
GG vs. TT+TG	Ethnicity	Asian	3	1.81(1.02,3.20)	0.042
		African–American	1	0.94(0.67,1.32)	0.708
		Caucasian	1	10.29(0.64,165.29)	0.100
	HWE status	negative	1	1.45(0.24,8.76)	0.687
		positive	4	1.47(0.80, 2.70)	0.220
rs5029937
T vs. G	Ethnicity	Caucasian	4	1.43(1.14,1.79)	0.002
		Asian	1	1.33(0.89,2.01)	0.168
GT+TT vs. GG	Ethnicity	Caucasian	4	1.43(1.12,1.82)	0.004
		Asian	1	1.33(0.87,2.04)	0.185

^*Bold values are statistically significant (P < 0.05)