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. 2017 Feb 15;8(13):20813–20824. doi: 10.18632/oncotarget.15343

Figure 8. Human tumors growth arrested in nude athymic mice treated with PJ34.

Figure 8

The growth of human triple negative breast MDA-MB-231 xenotransplants was significantly arrested in the indicated nude athymic mice injected i.p. (intraperitoneal) with PJ34 (60 mg/kg, daily for 14 days). The significance of the change in tumor growth rate was calculated by using one-tailed t-test for estimating the statistical significance of the difference between the group means, without assuming equal variance. The result was statistically significant: p = 0.036 (t = 2.14, df = 6.33). The daily measured average tumor size in each group is presented in Supplementary Figure 3.