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. 2017 Feb 15;8(13):20865–20880. doi: 10.18632/oncotarget.15348

Figure 2. Metformin abrogates the platelet-increased formation of capillary-like structures in matrigel (angiogenesis).

Figure 2

(A) EA.hy926 cells and HUVEC were seeded onto matrigel and incubated in the presence of control (vehicle), Metformin (20 μM), Platelets (150,000/ μL) and Metformin (20 uM) plus Platelets (150,000/ μL) for 12 hrs. (B) Quantified angiogenic score, n = 4. *P < 0.05 vs. control, #P < 0.05 vs. Platelets. One-way ANOVA followed by Tukey post-test.