Table 1. Effects of IDA on hepatotoxicity indices in CCl4-treated mice.
Groups | ALT (U/L) | AST (U/L) | Alb (g/dl) | TB (mg/dl) | TC (mg/dl) | TG (mg/dl) |
---|---|---|---|---|---|---|
Control | 21.4 ± 2.1 | 78.6 ± 4.2 | 4.1 ± 0.4 | 2.1 ± 0.3 | 26.7 ± 3.3 | 70.4 ± 6.2 |
IDA | 20.8 ± 3.3 | 79.3 ± 5.1 | 4.2 ± 0.3 | 2.3 ± 0.2 | 28.1 ± 2.4 | 71.2 ± 5.8 |
CCl4 | 68.5 ± 4.1a | 127.9 ± 7.3a | 2.8 ± 0.2a | 4.8 ± 0.4a | 88.5 ± 6.8a | 167.3 ± 9.5a |
CCl4 + IDA | 48.1 ± 3.0ab | 89.7 ± 5.6ab | 3.6 ± 0.3ab | 3.5 ± 0.3ab | 48.4 ± 4.3ab | 85.6 ± 7.8ab |
ALT, Alanine transaminase; AST, Aspartate transaminase; Alb, albumin; TB, total bilirubin; TC, total cholesterol; TG, triglycerides. ap < 0.05 versus Control; bp < 0.05 versus CCl4. Statistical analyses for two groups comparisons were performed using Student's t test. Statistical analysis for multiple group comparisons was performed using one-way analysis of variance (ANOVA) followed by Duncan's test.