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. 2017 Feb 19;8(13):21305–21314. doi: 10.18632/oncotarget.15515

Figure 5. Effect of BMMSC transplantation and G-SCF therapy on pancreatic mRNA expression following L-arginine–induced injury in rats.

Figure 5

(A) The gene expression levels of Nkx-6, Ngn3, and Pax-4 were determined using RT-PCR analysis at 3 weeks after BMMSC and G-SCF administration. (B) Ngn3 expression was higher in the BMMSC+G-SCF group than in the BMMSC group and G-CSF group (P < 0.05 vs. the control group). (C) The grey value ratio between Pax-4 and β-actin was 0.51 in the BMMSC+G-CSF group, as compared to 0.11 in the control group, 0.18 in the BMMSC group, and 0.192 in the G-CSF group (P < 0.05). (D) The grey value ratio between Nkx-6 and β-actin was 1.10 in the BMMSC+G-CSF group, compared to 0.21 in the control group, 0.73 in the BMMSC group, and 0.82 in the G-CSF group (P < 0.05).