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. 2017 Feb 20;8(13):21327–21335. doi: 10.18632/oncotarget.15570

Figure 2. Clinical description.

Figure 2

(A–B) Colonoscopy and histology of the proband (II-9). Polyps of colon is High grade intraepithelial neoplasia (dysplasia), cancer invade the submucosa in proband (II-9). A. Protrude type mass in retucm, the mass take up the whole enteric cavity. (B) Moderately differentiated adenocarcinoma. (C–D) Colonoscopy and histology of the other affected members (III-25). Polyps of colon, cancer invade the submucosa (III-25). (C) Multiple polyps. (D) Tubular adenoma. (E–F) No polyps in the colon of unaffected member with normal histology (III-12). (E) Smooth intestinal tract. (F) Chronic inflammation of mucosa.