Table 1. Clinical characteristics of all the affected and unaffected family members in this four generation Chinese family.
Family ID | Sex | WT/MT | Present Age (Years) | No. of Colorectal Adenomas or Polyps | Clinical Symptoms | Extra-colonic Features |
---|---|---|---|---|---|---|
I-1 | M | Died (80) | Unknown | Suspected FAP | ||
I-2 | F | Died (82) | Died due to heart disease | |||
II-1 | F | Died (79) | 100–1000 | Intestinal Cancer | ||
II-2 | M | WT | 75 | |||
II-3 | M | WT | 85 | - | ||
II-4 | F | WT | 80 | - | ||
II-5 | M | WT | 75 | |||
II-6 | F | WT | 70 | |||
II-7 | M | Died (70) | FAP(-) | Lung Cancer | ||
II-8 | F | WT | 65 | |||
II-9 | M | MT | 61 | 100–1000 | FAP/CRC | |
II-10 | F | WT | 59 | |||
III-1 | F | Died (40) | Died due to heart disease | |||
III-2 | F | WT | 53 | - | ||
III-3 | M | WT | 55 | - | ||
III-4 | M | WT | 54 | |||
III-5 | F | WT | 53 | |||
III-6 | M | MT | 50 | 100–1000 | FAP/CRC | |
III-7 | F | WT | 48 | |||
III-8 | M | MT | 42 | 100–1000 | FAP/CRC | |
III-9 | F | WT | 40 | |||
III-10 | M | WT | 49 | |||
III-11 | F | WT | 48 | |||
III-12 | M | WT | 47 | |||
III-13 | F | WT | 46 | |||
III-14 | M | WT | 47 | - | ||
III-15 | F | WT | 46 | - | ||
III-16 | M | WT | 42 | - | ||
III-17 | F | WT | 40 | - | ||
III-18 | M | WT | 48 | - | ||
III-19 | F | WT | 47 | - | ||
III-20 | M | WT | 46 | - | ||
III-21 | F | WT | 46 | |||
III-22 | M | WT | 45 | |||
III-23 | F | WT | 43 | |||
III-24 | M | WT | 32 | |||
III-25 | F | MT | 30 | 100–1000 | FAP | |
IV-1 | M | WT | 34 | |||
IV-2 | M | WT | 30 | |||
IV-3 | F | WT | 26 | |||
IV-4 | F | WT | 26 | |||
IV-5 | M | WT | 24 | |||
IV-6 | F | WT | 24 | |||
IV-7 | M | WT | 23 | |||
IV-8 | F | WT | 20 | |||
IV-9 | M | WT | 18 | |||
IV-10 | F | WT | 18 | |||
IV-11 | F | WT | 20 | |||
IV-12 | M | WT | 20 | |||
IV-13 | M | WT | 5 |