Figure 4. Effects of ipilimumab treatment on naïve (A-B), CM (C-D), EM (E-F) and EMRA (G-H) CD4+ T cell memory subsets.

(A-D) data from the full patient cohort; (E-H) when possible, matched analysis of complete sample sets (baseline, 3w and 9w) was performed. Each dot represents an individual patient; mean ±95% CI are represented *, P<0.05; **, P<0.001; ***, P<0.0001