Figure 2. Gene network remodeling was involved in lung cancers under hypoxia conditions.

A. A volcano plot compared gene expression in hypoxic and normoxic fragments of lung cancer. B. Graphic display of the gene expression profiles in a heat-map format from hypoxic and normoxic fragments of lung cancer. C, D, E. The pathways and gene ontology were significantly affected by hypoxia. F. Genes were significantly regulated by hypoxia in metabolic pathways. G. Network of gene pathway for differentially expressed transcription factors. H. Gene network for the differentially expressed metabolic pathway.