Table 2. Univariate Cox proportional hazards analysis of KLF gene expression and overall survival for patients with CRC in the TCGA cohort.

Factor	Univariate analysis*			Multivariate analysis
	HR	95% CI	P	HR	95% CI	P
Gender	0.675	0.415-1.099	0.114
Age	1.025	1.005-1.046	0.013	1.034	1.013-1.056	0.001
T category	1.778	0.900-3.510	0.097
N stage	1.736	1.333-2.259	<0.001	1.535	1.155-2.042	0.003
M stage	2.620	1.823-3.765	<0.001	2.250	1.472-3.439	<0.001
KLF1	1.055	0.780-1.428	0.730
KLF2	1.195	0.962-1.483	0.107
KLF3	0.501	0.272-0.920	0.025	0.437	0.230-0.831	0.012
KLF4	0.798	0.633-1.006	0.056
KLF5	0.879	0.605-1.277	0.498
KLF6	0.903	0.627-1.301	0.583
KLF7	1.033	0.832-1.283	0.766
KLF8	1.139	0.923-1.406	0.224
KLF9	1.077	0.864-1.343	0.509
KLF10	0.951	0.660-1.369	0.786
KLF11	1.075	0.723-1.598	0.719
KLF12	1.164	0.968-1.400	0.106
KLF13	0.673	0.638-1.337	0.924
KLF14	1.454	1.059-1.995	0.020	1.210	0.838-1.748	0.309
KLF15	1.082	0.933-1.254	0.300
KLF16	1.129	0.659-1.934	0.658
KLF17	1.241	1.030-1.494	0.023	1.101	0.868-1.398	0.427

*Abbreviations: CI, confidence interval; HR, hazard ratio.

** Bold type indicates statistical significance.