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The phosphorylation of P53 on serine 15 and of H2AX histone on serine 139 was monitored by western blot analyses in three mice at days 6 and 19 for each group and at day 13 for DOTA-Ts29.2 and [177Lu]DOTA-Ts29.2 groups (upper part). The level of phosphorylated proteins was normalized by GAPDH as a loading control (lower part).
