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. 2017 Mar 6;8(13):22059–22075. doi: 10.18632/oncotarget.15908

Figure 4. Western blots of the proteins of PDGF-B signaling pathway.

Figure 4

The different expressions from three individual patients are presented for the selected proteins. PDGF-B, PDGFR-β, eIF4E and p70s6K were increased in the gastric cancer tissues, compared to normal gastric tissues, Akt expression is increased in two groups, ERK1/2 expression was not significantly altered. The phosphorylation and activation status of Akt, ERK, p70S6K and eIF4E were observed significantly increased. All the experiments were repeated at least three times, N represents normal tissue and T represents tumor tissue.