Table 5.

Prevalence of carrying at least one minor allele of genes involved in the immune response in men with or without inflammation, controls in the finasteride arm, Prostate Cancer Prevention Trial

Gene	SNPs	Minor allele	Intraprostatic inflammationa				Pb
			None		Yes
			Number of carriers/total	Prevalence of carriers (%)	Number of carriers/total	Prevalence of carriers (%)
IL1β	rs1143634	T	6/13	46.15	78/169	46.14	0.9
IL1β	rs1143627	C	6/12	50.00	91/170	53.53	0.8
IL2	rs2069762	G	6/13	46.15	93/174	53.45	0.6
IL4	rs2243250	T	3/12	25.00	39/165	23.64	0.9
IL6	rs1800795	C	11/13	84.62	112/170	65.88	0.2
IL6	rs1800797	A	11/13	84.62	108/170	63.53	0.1
IL8	rs4073	A	8/13	61.54	136/174	78.16	0.2
IL10	rs1800871	T	2/12	16.67	58/164	35.37	0.2
IL10	rs1800872	A	2/13	15.38	65/173	37.57	0.1
IL10	rs1800896	G	11/13	84.62	125/172	72.67	0.3
IL10	rs3024496c	C	10/12	83.33	128/174	73.56	0.5
IL10	rs1800894c	A	0/13	0.00	11/174	6.32	0.9d
IL10	rs1800890c	A	10/13	76.92	111/169	65.68	0.4
IL10	rs3024509c	C	1/13	7.69	20/169	11.83	0.7
IL10	rs1554286c	T	2/13	15.38	50/174	28.74	0.3
IL10	rs3021094c	C	0/13	0.00	31/174	17.82	0.1d
IL10	rs3024498c	G	9/12	75.00	89/168	52.98	0.1
IL12(p40)	rs3212227	C	4/13	30.77	65/170	38.24	0.6
IFNG	rs2430561	A	9/12	75.00	115/163	70.55	0.7
MSR1	rs3747531	C	0/12	0.00	19/173	10.98	0.6d
RNASEL	rs486907	A	11/13	84.62	109/170	64.12	0.1
TLR4	rs4986790	G	1/13	7.69	21/173	12.14	0.6
TNFA	rs1800629	A	6/13	46.15	59/173	34.10	0.4

^aAt least one biopsy core with inflammation of an average of three reviewed

^bChi-square

^cTagSNPs

^dFisher’s exact test