Fig. 5. SR1001 or IL-17 antibody treatment decreases EMT in mouse prostate tumors.
A-F: Representative prostate sections from SR1001 and DMSO-treated mice stained for EMT markers. Arrows indicate positive staining cells. H-M: Representative prostate sections from IL-17 antibody and control IgG-treated mice stained for EMT markers; arrows indicate positive staining cells. G and N: Quantification of EMT markers staining; Total Score (TS) = Proportion Score (PS, range 0 - 5) + Intensity Score (IS, rang 0 - 3); data are represented as mean ± s.e.m., n = 3 animals per group, *P < 0.05, **P < 0.01.