Table 1.
Hemoglobin, systemic and intestinal hemodynamic and oxygen transport variables, and arterial blood gases in hemorrhage/retransfusion (H/R) and sham groups
| Hemorrhage | Retransfusion | |||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | 30′ | 60′ | 90′ | 2′ | 30′ | 60′ | ||
| Hemoglobin (g per 100 mL) | H/R | 8.3 [7.7–9.7] | 7.8 [7.3–9.1]† | 7.3 [7.0–9.1]*† | 6.5 [6.1–7.7]*† | 8.0 [6.9–9.3]† | 7.8 [7.7–9.7] | 8.1 [7.2–9.7] |
| Sham | 9.9 [9.3–10.3] | 9.9 [9.5–10.4] | 9.8 [9.3–10.5] | 9.6 [9.2–9.8] | 9.6 [9.2–9.8] | 9.3 [8.8–9.8] | 9.4 [8.6–10.0] | |
| Mean arterial pressure (mmHg) | H/R | 83 [72–96] | 42 [34–47]*† | 40 [32–44]*† | 28 [22–30]*† | 95 [90–100] | 90 [82–99] | 91 [79–97] |
| Sham | 91 [90–102] | 97 [80–109] | 92 [89–102] | 99 [91–109] | 98 [90–108] | 100 [92–112] | 100 [91–110] | |
| Central venous pressure (mmHg) | H/R | 3 [0–6] | 3 [1–6] | 4 [1–7] | 4 [0–7] | 6 [1–9] | 3 [1–5] | 3 [0–5] |
| Sham | 2 [1–2] | 2 [1–4] | 3 [1–3] | 2 [1–4] | 2 [1–4] | 2 [1–4] | 2 [1–4] | |
| Mean pulmonary pressure (mmHg) | H/R | 17 [10–20] | 12 [7–17] | 11 [8–13] | 10 [6–12]*† | 22 [17–32]† | 18 [12–20] | 16 [13–19] |
| Sham | 11 [10–13] | 13 [12–14] | 14 [13–15] | 13 [12–13] | 13 [12–13] | 14 [13–15] | 13 [11–16] | |
| Pulmonary occlusion pressure (mmHg) | H/R | 5 [4–7] | 6 [1–8] | 4 [1–8] | 6 [0–7] | 7 [4–9] | 5 [2–9] | 4 [2–7] |
| Sham | 3 [2–6] | 2 [2–4] | 2 [2–3] | 3 [3–4] | 3 [3–4] | 2 [1–4] | 2 [2–3] | |
| Cardiac index (mL min−1 kg−1) | H/R | 155 [136–177] | 89 [64–177] | 78 [70–119] | 53 [39–72]*† | 210 [158–340]† | 133 [116–179] | 134 [102–180] |
| Sham | 122 [101–149] | 122 [100–151] | 108 [97–167] | 99 [94–168] | 101 [96–112] | 110 [99–178] | 113 [96–174] | |
| Mesenteric flow (mL min−1 per 100 g) | H/R | 805 [489–903] | 451 [253–665] | 427 [264–576] | 236 [110–332]*† | 1052 [644–1406]† | 850 [550–1072] | 923 [523–986] |
| Sham | 457 [445–786] | 500 [457–992] | 445 [426–743] | 457 [379–714] | 448 [428–750] | 487 [457–892] | 502 [487–814] | |
| Arterial pH | H/R | 7.44 [7.35–7.49] | 7.44 [7.39–7.49] | 7.44 [7.40–7.49] | 7.42 [7.39–7.48] | 7.28 [7.20–7.37]*† | 7.37 [7.29–7.43]† | 7.41 [7.32–7.45]† |
| Sham | 7.49 [7.42–7.51] | 7.49 [7.39–7.56] | 7.52 [7.41–7.52] | 7.53 [7.42–54] | 7.52 [7.41–7.53] | 7.51 [7.44–55] | 7.55 [7.42–54] | |
| Arterial PCO2 (mmHg) | H/R | 38 [37–40] | 36 [35–39] | 36 [33–39] | 34 [31–36]* | 44 [41–52]*† | 38 [36–42] | 39 [34–41] |
| Sham | 38 [33–40] | 37 [35–40] | 36 [34–39] | 34 [33–39] | 34 [33–39] | 34 [32–38] | 34 [32–38] | |
| Arterial PO2 (mmHg) | H/R | 86 [77–91] | 83 [77–93] | 88 [77–95] | 92 [87–106] | 75 [69–84]*† | 86 [75–92] | 85 [77–94] |
| Sham | 87 [78–93] | 83 [81–87] | 87 [83–95] | 87 [78–99] | 91 [74–99] | 88 [87–100] | 89 [85–99] | |
| Arterial bicarbonate (mEq L−1) | H/R | 26 [21–28] | 25 [22–27] | 23 [20–26]* | 23 [18–25]*† | 23 [18–25]*† | 23 [19–25]*† | 24 [19–27]† |
| Sham | 26 [25–28] | 29 [23–31] | 28 [25–29] | 27 [25–29] | 27 [25–29] | 27 [25–28] | 28 [25–30] | |
| Arterial base excess (mEq L−1) | H/R | 2 [−4 to 4] | 1 [−2 to 5] | 2 [−2 to 3] | −1 [−5 to 3]*† | −3 [−9 to 0]*† | −2 [−6 to 1]*† | −1 [−6 to 2]† |
| Sham | 3 [−3 to 5] | 5 [−2 to 9] | 5 [1–6] | 4 [0–6] | 4 [0–6] | 4 [0–5] | 5 [1–8] | |
Data are shown as median [percentile 0.25–0.75]
*P < 0.05 vs. basal; †P < 0.05 vs. sham