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Journal of the Royal College of Physicians of London logoLink to Journal of the Royal College of Physicians of London
. 1994 May-Jun;28(3):209–219.

Nitric Oxide - From Mediator to Medicines

Patrick Vallance 1, Salvador Moncada 2
PMCID: PMC5400981  PMID: 7523666

Abstract

Nitric oxide is involved in a wide range of physiological processes in humans and in animals. It controls vascular tone, acts as a neurotransmitter and neuromodulator in the central and peripheral nervous systems and influences the activity of the immune system. Substances that selectively enhance or inhibit its synthesis or removal and modify its effects, are likely to yield interesting therapeutic agents.

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Contributor Information

Patrick Vallance, Senior Lecturer in Clinical Pharmacology, St George's Hospital Medical School, London.

Salvador Moncada, Research Director, Wellcome Research Laboratories, Beckenham.


Articles from Journal of the Royal College of Physicians of London are provided here courtesy of Royal College of Physicians

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