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. 2005 Jan;43(1):458–461. doi: 10.1128/JCM.43.1.458-461.2005

TABLE 2.

Characteristics of blaIMP-containing non-imipenem-susceptible P. aeruginosa isolates

Strain Hospital no. Material Type of enzyme Patternb Integron structurec MIC (μg/ml)a
CAZ IPM MEM LVX AZT AMK NET GEN KAN ABK
TUM1672 1 Urine VIM-2-like A I 64 >128 >128 16 32 0.06 0.5 0.5 8 0.06
TUM1673 1 Sputum IMP-1-like B II >128 8 32 16 8 64 >128 4 >128 16
TUM1682 2 Sputum IMP-1-like C III >128 64 >128 32 32 32 >128 2 >128 2
TUM1683 2 Sputum IMP-1-like D IV >128 64 >128 32 64 16 >128 2 >128 2
TUM1708 3 Urine IMP-1-like D IV >128 64 >128 32 32 32 >128 4 >128 4
TUM1709 3 Urine IMP-1-like D IV >128 64 >128 32 32 32 >128 4 >128 2
TUM1710 3 Urine IMP-1-like D IV >128 64 >128 32 64 32 >128 2 >128 4
TUM1721 4 Urine IMP-1-like E V >128 64 >128 32 32 32 >128 >128 >128 64
TUM1732 5 Urine IMP-1-like D IV >128 64 >128 32 128 32 >128 4 >128 2
TUM1733 5 Pus IMP-1-like F VI >128 64 >128 64 32 2 >128 >128 >128 1
TUM1757 6 Sputum IMP-1-like G VII >128 64 >128 16 16 32 >128 1 >128 16
a

CAZ, ceftazidime; IPM, imipenem; MEM, meropenem; LVX, levofloxacin; AZT, aztreonam; AMK, amikacin; NET, netilmicin; GEN, gentamicin; KAN, kanamycin; ABK, arbekacin.

b

PEGE profiles obtained with Spe1 chromosomal digestion of P. aeruginosa carrying a metallo-β-lactamase gene as recommended by Tenover et al. (15).

c

Integron structures possessed by each gene as mentioned in the text. I, blaVIM-2-like, aacA4 and aadA2; II, blaIMP-1-like, aadA1 and orfG; III, blaIMP-1-like, aadA1 and unknown gene; IV, blaIMP-1-like, aadA1 and unknown gene; V, blaIMP-1-like, aacA4, aadA1 and blaOXA-2; VI, blaIMP-1-like, aacA4; VII, only blaIMP-1-like gene.