TABLE 2.
Results obtained with antibiotic combinations by checkerboard method
Strain no. | RIF-DOX
|
RIF-SXT
|
SXT-DOX
|
SM-DOX
|
AZM-CIP
|
|||||
---|---|---|---|---|---|---|---|---|---|---|
ΣFIC | Activitya | ΣFIC | Activity | ΣFIC | Activity | ΣFIC | Activity | ΣFIC | Activity | |
1 | 0.50 | S | 4.24 | A | 4 | A | 2.12 | A | 0.27 | S |
2 | 0.37 | S | 0.37 | S | 2.5 | A | 0.31 | S | 1.32 | I |
3 | 1.03 | I | 0.56 | I | 2.5 | A | 0.18 | S | 0.12 | S |
4 | 0.15 | S | 0.18 | S | 0.51 | I | 0.26 | S | 0.31 | S |
5 | 0.31 | S | 1.12 | I | 1.03 | I | 0.49 | S | 0.53 | I |
6 | 2.06 | A | 2.50 | A | 4.03 | A | 1.03 | I | 0.02 | S |
7 | 1.08 | I | 2.12 | A | 1.7 | I | 0.56 | A | 0.52 | I |
8 | 0.13 | S | 0.51 | I | 8.06 | A | 0.28 | S | 0.36 | S |
9 | 4.03 | A | 2.25 | A | 1.08 | I | 0.75 | A | 0.12 | S |
10 | 0.36 | S | 2.03 | A | 0.28 | S | 1.10 | I | 0.18 | S |
11 | 0.27 | S | 2.06 | A | 0.53 | I | 0.24 | S | 0.13 | S |
12 | 0.62 | I | 0.57 | I | 0.31 | S | 0.56 | I | 0.62 | I |
13 | 1.25 | I | 0.51 | I | 0.18 | S | 0.36 | S | 4.25 | A |
14 | 0.28 | S | 1.08 | I | 0.56 | I | 4.15 | A | 0.31 | S |
15 | 0.31 | S | 1.12 | I | 0.28 | S | 0.62 | I | 0.04 | S |
16 | 0.13 | S | 0.51 | I | 5.0 | A | 4.12 | A | 2.06 | A |
S, synergy; A, antagonism; I, indifference.