Table 1.

Indirect indicators related to breast cancer diagnosis in DCs.

PICOT		Factor	Indicator
Population	Breast cancer	Epidemiological	Incidence of breast cancer
Intervention	Methodology or diagnostic condition	Diagnosis	Diagnostic strategy methodology National Guidelines; Screening age range Mammography infrastructure; % of population coverage % of mammographies performed Structuring of network with screening rounds
		Quality	Form of presentation of symptoms at diagnosis Time to diagnosis % of early-stage cases (CS 0, CS 0+1, localized/regional disease)
Comparator	Control		Trend curves/temporal data Vulnerable subpopulations Comparison among countries
Outcome	Final outcome	Survival	Mortality/incidence ratio Survival according to staging

CS = clinical stage.