Table 5.
Association of hs-cTnT with incident HF
| Categories of hs-cTnT (ng/L) | Event Rate (/1000 p-yrs) | Unadjusted Hazard Ratios | Demographic adjusted | + risk factors* | + LVM & LVEF | +NT-proBNP |
|---|---|---|---|---|---|---|
| <LOD | Reference | Reference | Reference | Reference | Reference | |
| 3.0–4.25 | 0.8 (0.5, 1.3) | 1.72 (0.82, 3.61) |
1.32 (0.62, 2.79) |
1.75 (0.85, 3.62) |
1.60 (0.78, 3.30) |
1.60 (0.77, 3.29) |
| 4.26–5.87 | 1.7 (1.0, 2.8) | 2.61 (1.34, 5.10) |
1.75 (0.88, 3.47) |
1.74 (0.86, 3.50) |
1.53 (0.76, 3.10) |
1.57 (0.77, 3.17) |
| 5.88–8.80 | 2.1 (1.3, 3.2) | 5.38 (2.96, 9.75) |
2.98 (1.60, 5.58) |
2.27 (1.18, 4.44) |
1.75 (0.90, 3.42) |
1.70 (0.87, 3.34) |
| ≥8.81 | 11.7 (9.6, 14.3) |
14.13 (8.18, 24.4) |
6.45 (3.54, 11.79) |
5.59 (2.97, 10.68) |
3.47 (1.80, 6.68) |
2.93 (1.50, 5.67) |
| Test for trend | <.001 | <.001 | <.001 | <.001 | <.001 | .001 |
| ln(hs-cTnT) | N/A | 3.12 (2.69, 3.63) |
2.59 (2.15, 3.13) |
2.35 (2.00, 2.78) |
1.88 (1.50, 2.35) |
1.55 (1.23, 1.95) |
Risk factors: SBP, DBP, anti-hypertensive medications, diabetes (normal/DM), smoking, lipids, height, weight, and estimated GFR.
Cell values represent Hazard Ratios (95% CI).