Table 2.
Control group | GDM | p valuea | p valuea | OR (95% CI) | ||||
---|---|---|---|---|---|---|---|---|
n | % | n | % | |||||
ADIPOQ rs266729 genotype | ||||||||
CC | 115 | 55.56 | 92 | 45.10 | 0.11 | GG + CG vs CC | 0.034 | 1.52 (1.03–2.25) |
CG | 75 | 36.23 | 91 | 44.61 | GG vs CG + CC | 0.47 | 1.28 (0.66–2.51) | |
GG | 17 | 8.21 | 21 | 10.29 | GG vs CC | 0.22 | 1.54 (0.77–3.10) | |
CG vs CC | 0.046 | 1.52 (1.01–2.29) | ||||||
GG vs CG | 0.96 | 1.02 (0.50–2.07) | ||||||
Allele | ||||||||
C | 305 | 73.67 | 275 | 67.40 | ||||
G | 109 | 26.33 | 133 | 32.60 | G vs C | 0.049 | 1.35 (1.00–1.83) | |
ADIPOQ rs1501299 genotype | ||||||||
GG | 106 | 51.21 | 98 | 48.04 | 0.76 | TT + GT vs GG | 0.52 | 1.14 (0.77–1.67) |
GT | 83 | 40.10 | 85 | 41.67 | TT vs GT + GG | 0.58 | 1.20 (0.62–2.33) | |
TT | 18 | 8.70 | 21 | 10.29 | TT vs GG | 0.51 | 1.26 (0.63–2.51) | |
GT vs GG | 0.62 | 1.11 (0.74–1.67) | ||||||
TT vs GT | 0.71 | 1.14 (0.57–2.29) | ||||||
Allele | ||||||||
G | 295 | 71.26 | 281 | 68.87 | ||||
T | 119 | 28.74 | 127 | 31.13 | T vs G | 0.46 | 1.12 (0.83–1.51) | |
LEP rs2167270 genotype | ||||||||
GG | 76 | 36.71 | 77 | 37.75 | 0.83 | AA + GA vs GG | 0.83 | 0.96 (0.64–1.43) |
GA | 102 | 49.28 | 95 | 46.57 | AA vs GA + GG | 0.63 | 1.14 (0.66–1.97) | |
AA | 29 | 14.01 | 32 | 15.69 | AA vs GG | 0.78 | 1.09 (0.60–1.97) | |
GA vs GG | 0.70 | 0.92 (0.60–1.40) | ||||||
AA vs GA | 0.56 | 1.18 (0.67–2.11) | ||||||
Allele | ||||||||
G | 254 | 61.35 | 249 | 61.03 | ||||
A | 160 | 38.65 | 159 | 38.97 | A vs G | 0.92 | 1.01 (0.77–1.34) |
HWE: control group p = 0.37, GDM p = 0.87 for ADIPOQ rs266729
HWE: control group p = 0.74, GDM p = 0.74 for ADIPOQ rs1501299
HWE: control group p = 0.66, GDM p = 0.77 for LEP rs2167270
a χ 2 test