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. 2017 Jan 3;34(4):511–516. doi: 10.1007/s10815-016-0866-2

Table 2.

Distribution of ADIPOQ and LEP genotypes in GDM women and control group

Control group GDM p valuea p valuea OR (95% CI)
n % n %
ADIPOQ rs266729 genotype
 CC 115 55.56 92 45.10 0.11 GG + CG vs CC 0.034 1.52 (1.03–2.25)
 CG 75 36.23 91 44.61 GG vs CG + CC 0.47 1.28 (0.66–2.51)
 GG 17 8.21 21 10.29 GG vs CC 0.22 1.54 (0.77–3.10)
CG vs CC 0.046 1.52 (1.01–2.29)
GG vs CG 0.96 1.02 (0.50–2.07)
Allele
 C 305 73.67 275 67.40
 G 109 26.33 133 32.60 G vs C 0.049 1.35 (1.00–1.83)
ADIPOQ rs1501299 genotype
 GG 106 51.21 98 48.04 0.76 TT + GT vs GG 0.52 1.14 (0.77–1.67)
 GT 83 40.10 85 41.67 TT vs GT + GG 0.58 1.20 (0.62–2.33)
 TT 18 8.70 21 10.29 TT vs GG 0.51 1.26 (0.63–2.51)
GT vs GG 0.62 1.11 (0.74–1.67)
TT vs GT 0.71 1.14 (0.57–2.29)
Allele
 G 295 71.26 281 68.87
 T 119 28.74 127 31.13 T vs G 0.46 1.12 (0.83–1.51)
LEP rs2167270 genotype
 GG 76 36.71 77 37.75 0.83 AA + GA vs GG 0.83 0.96 (0.64–1.43)
 GA 102 49.28 95 46.57 AA vs GA + GG 0.63 1.14 (0.66–1.97)
 AA 29 14.01 32 15.69 AA vs GG 0.78 1.09 (0.60–1.97)
GA vs GG 0.70 0.92 (0.60–1.40)
AA vs GA 0.56 1.18 (0.67–2.11)
Allele
 G 254 61.35 249 61.03
 A 160 38.65 159 38.97 A vs G 0.92 1.01 (0.77–1.34)

HWE: control group p = 0.37, GDM p = 0.87 for ADIPOQ rs266729

HWE: control group p = 0.74, GDM p = 0.74 for ADIPOQ rs1501299

HWE: control group p = 0.66, GDM p = 0.77 for LEP rs2167270

a χ 2 test