Table 1.
Results of oocyte vitrification/warming and ICSI, embryo culture, PGS-A analysis, and clinical outcomes from vitrified/warmed and fresh oocytes
| Vitrified/warmed oocytes (first ovarian stimulation) | Fresh oocytes (second ovarian stimulation) | p | |
|---|---|---|---|
| N. patients | 69 | 69 | |
| N. ovarian cycles to accumulate oocytes | 82 | 69 | |
| In vitro results | |||
| Metaphase II oocytes at OPU (mean per OPU) | 615 (7.5) | 463 (6.7) | |
| Vitrified oocytes | 615 | – | |
| Survived oocytes (survival rate) | 591 (96.1) | – | |
| Micro-injected oocytes | 591 | 463 | |
| Zygotes (fertilization rate) | 411 (69.5) | 343 (74.1) | NS |
| Expanded/hatching biopsied Blastocysts (proportion on zygote) | 138 (33.3) | 135 (39.4) | NS |
| Vitrified biopsied blastocysts | 138 | 135 | |
| Genetic testing results | |||
| Completed genetic analysis (percentage) | 134 (97.1) | 130 (96.3) | NS |
| N. euploid blastocysts (euploidy rate on completed genetic analysis) | 57 (42.5) | 53 (40.8) | NS |
| N. aneuploid blastocysts (aneuploidy rate on completed genetic analysis) | 77 (57.5) | 77 (59.2) | NS |
| Euploid/aneuploid blastocyst rate per initial MII oocytes | 9.3/12.5 | 11.4/16.6 | NS/0.05 |
| Clinical outcomes | |||
| Warmed, survived and transferred blastocysts | 25 | 46 | |
| Embryo transfers | 25 | 46 | |
| Clinical pregnancies (per embryo transfer) | 15 (60.0) | 30 (65.2) | NS |
| Implanted embryos (implantation rate) | 14 (56.0) | 28 (60.9) | NS |
| Arrested pregnancy | 1 | 2 | |
NS non-significant