Table 3.

Genotype distributions of female and male partners in the RPL cohort according to fetal losses categories of miscarriage

Genotype	All 1° and 2°	RPL	Subgroup 1: early fetal losses, ≤15th GW		Subgroup 2: late fetal losses, >15 GW		Population controls	Parous controls
	Women n (%)	Men n (%)	Women n (%)	Men n (%)	Women n (%)	Men n (%)	n (%)	n (%)
Genotypes	n = 179	n = 107	n = 171	n = 102	n = 8	n = 5	n = 360	n = 166
N/N	88 (49.2)	49 (45.8)	83 (48.5)	46 (45.1)	5 (62.5)	3 (0.6)	208	108 (65.1)
N/M2	83 (46.4)	55 (51.4)	80 (46.8)	53 (51.9)	3 (37.5)	2 (0.4)	134	46 (27.7)
M2/M2	8 (4.5)	3 (2.8)	8 (4.7)	3 (3.0)	0 (0.0)	0 (0.0)	18	12 (7.2)
M2 AF	0.277	0.285	0.281	0.289	0.188	0.200	0.236	0.211
M2 carriage	91 (50.9)	58 (54.2)	88 (51.5)	56 (54.9)	3 (37.5)	2 (33.3)	134 (42.2)	58 (34.9)

RPL recurrent pregnancy loss, N “normal” allele including M1 heterozygous and homozygous combinations, AF allele frequency, GW gestational week