Table 3.

Fold change expression of extracellular miRNAs in follicular fluid containing normally versus abnormally fertilized oocytes

miRNAa	Fold change	Normally fertilized (n = 30)	Abnormally fertilized (n = 4)	P value
hsa-miR-454-5p	0.25	13	2	<0.0001
hsa-miR-425-3p	0.32	10	2	0.001
hsa-miR-16-5p	0.38	13	2	0.003
hsa-miR-222-3p	0.34	4	2	0.04
hsa-miR-520f-3p	9.18	9	3	0.09
hsa-miR-30d-5p	0.52	30	4	0.12
hsa-miR-19b-3p	0.36	8	2	0.12
hsa-miR-223-5p	0.47	16	3	0.14
hsa-miR-10b-3p	15.84	26	4	0.17
hsa-miR-1255b-5p	0.36	22	4	0.18
hsa-miR-1226-5p	0.65	22	4	0.18
hsa-miR-663b	0.16	22	3	0.21
hsa-miR-380-5p	0.52	21	4	0.24
hsa-miR-720	0.64	25	3	0.32
hsa-miR-151a-5p	1.93	11	3	0.47
hsa-miR-206	0.28	21	2	0.50
hsa-miR-26a-1-3p	0.36	15	2	0.54
hsa-miR-572	0.53	25	2	0.59
hsa-miR-7-1-3p	1.19	24	4	0.62
hsa-miR-649	0.42	11	2	0.62

^aWe only show the top-20 miRNAs by p value. The full list of miRNAs is shown in Table S4 (Supplemental Material)