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. 2016 Sep 19;23(2):235–245. doi: 10.1007/s10989-016-9555-3

Table 3.

Effect of analyzed compounds on fibrinolysis parameters—thromboelastometric data

Compounds LOT (s) LT (min) LI30–LI45–LI60 (%)
Control 1993 ± 111 48 ± 4 91–39–2
H–EACA–OH ≥4084 ≥168 100–98–92
H–EACA–NH2 2488 ± 172 71 ± 5 96–80–32
H–Ala–Phe–Lys–EACA–NH2 2731 ± 160 76 ± 6 99–86–43
H–D-Ala–Phe–Lys–EACA–NH2 2519 ± 176 72 ± 4 97–79–28

LOT lysis onset time—time from the start of coagulation to the point which the amplitude of formed clot is reduced by 15 % (s). LT lysis time, when clot is reduced/lysed by 90 % (s). LI30–LI45–LI60 Lysis index amplitude of clot (%) after 30, 45, 60 min (%). Control without synthesized peptides