Fig. 5.

a Bar graph shows the representative data (%) of Bcl-2 levels in WSU-NHL, Hut-78 and Jeko-1 cells, evaluated by flow cytometry (*p = 0.001; **p = 0.009; ***p = 0.002). b Drug combination mediated the down regulation of anti-apoptotic proteins and phosphorylation of the pro-apoptotic proteins. Whole-cell lysates were subjected to western blotting using the indicated Abs. Tubulin was used to normalize protein loading. c Representative western blot for caspases-8, -9, -3 and PARP with or without ZVAD in cellular extracts from WSU-NHL, Hut-78 and Jeko-1 cells. Tubulin is shown as a loading control