Average samples during scheduled sleep (black box) and scheduled wakefulness for baseline days (filled symbols) and entrainment protocol days (open symbols) for synchronized (left panels) and not-synchronized (right panels) groups. Sample sizes were n=6, 5, 5, and 6 for synchronized, and n=7, 7, 7, and 6 for not-synchronized groups for TNF, IL-10, TNF/IL-10 ration and CRP, respectively. * denote significant differences between days within group for that time of day (p<0.0239).