Table 3.
HISTOLOGY & CLINICAL DATA | MILD PHENOTYPE | SEVERE PHENOTYPE | p value |
---|---|---|---|
Bile duct paucity (n=86) | (33/86) 39% | (53/86) 61% | 0.31 |
Bile duct proliferation (n=15) | (7/15) 44% | (8/15) 56% | 1.00 |
Cholestasis (on liver biopsy; n=80) | (28/80) 38% | (52/80) 62% | 0.04 |
Fibrosis (on liver biopsy; n=61) | (20/61) 32% | (41/61) 68% | <0.01 |
Pruritus (n=82) | (36/82) 43% | (46/82) 57% | 0.10 |
Xanthomata (n=32) | (8/32) 25% | (24/32) 75% | <0.01 |
Only a subset of the variables assessed is shown in this table.