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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Neurobiol Aging. 2017 Mar 17;54:40–53. doi: 10.1016/j.neurobiolaging.2017.01.025

Figure 2. Paraventricular nucleus of the hypothalamus gene expression Experiment 1.

Figure 2

Experiment 1 paraventricular nucleus of the hypothalamus gene expression for (A) Interleukin-6, (B) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IκBα), (C) Interleukin-1β, (D) Tumor Necrosis Factor α, (E) c-Fos, (F) Cluster of differentiation 14 (CD14), and (G) Monocyte chemoattractant protein-1 (MCP-1). Tissue was collected either 3 or 18 h after 3.0 g/kg intraperitoneal ethanol injection (Vehicle animals injected with saline at both time points and combined). All data are expressed relative to the ultimate control group (Male Vehicle) and normalized to CyclophilinA. Main effect of Drug (all p < 0.05) is indicated with an asterisk (*) to indicate significant differences in the 3 h EtOH group as compared to Vehicle and 18 h EtOH. Significant interaction of Drug × Sex is indicated by a lettering system in which bars that share a common letter are considered statistically comparable, whereas bars that do not share a common letter are identified as significantly different. All post-hoc comparisons were made using Fisher’s Least Significant Difference post hoc test (p < 0.05).