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Nuclear-specific AR-V7 localization improves prognostication of overall survival (OS) for patients on ARSi therapy. OS is shown for patient samples stratified by pre-ARSi AR-V7 status (n = 128) determined according to (A) nuclear-specific localization and (B) nuclear-agnostic localization and stratified by pre-taxane AR-V7 status (n = 63) determined according to (C) nuclear-specific localization and (D) nuclear-agnostic localization. ARSi = androgen receptor signaling inhibitor.
