Table 3.

Pooled hazard ratios of intermediate and advanced AMD according to cumulative average intake of fish

Fish‡	Servings/wk Median	Multivariate HR (95% CI)
		Almost never	1–3 servings/mo	1 serving/wk	2–4 servings/wk	≥ 5 servings/wk	p trend
Intermediate AMD
Canned tuna	0.70	1 (ref)	0.94 (0.83,1.07)	0.84 (0.73, 0.96)		0.68 (0.44,1.05)	0.005
Dark fish	0.20	1 (ref)	1.08 (0.91,1.27)	0.92 (0.74, 1.14)			0.74
Other fisha	0.58	1 (ref)	0.96 (0.85,1.09)	0.91 (0.79, 1.05)		0.91 (0.45,1.83)	0.25
Total fatty fishb	0.98	1 (ref)	0.92 (0.80,1.06)	0.95 (0.82,1.10)	0.79 (0.65,0.96)	0.61 (0.46,0.81)	<.001
Advanced AMD
Canned tuna	0.70	1 (ref)	1.10 (0.96,1.26)	1.00 (0.86,1.16)		0.76 (0.46,1.23)	0.34
Dark fish	0.20	1 (ref)	1.04 (0.87,1.24)	0.98 (0.78,1.23)			0.97
Other fisha	0.58	1 (ref)	1.08 (0.94,1.23)	1.04 (0.89,1.22)		1.00 (0.44,2.24)	0.63
Total fatty fishb	0.98	1 (ref)	1.10 (0.94,1.29)	1.05 (0.90,1.24)	0.99 (0.80,1.22)	0.80 (0.59,1.08)	0.11

^‡Multivariate models were adjusted for the same variable as in Table 2

^aOther fish were mainly white fish

^bTotal fatty fish was the sum of canned tuna and dark fish. Finer intake categories were created to show detailed associations