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. 2017 Apr 24;11:108. doi: 10.3389/fncel.2017.00108

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Copyright © 2017 Shimaoka, Song and Knöpfel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of global wave events (GWEs). (A) Fluorescence image of a transgenic mouse brain (mCitrine channel) mounted on schematic outline of the mouse head. (B) Upper panel. Scan of color coded, high-pass (>0.5 Hz) filtered voltage signals along the red dotted line in (A). Lower panel. Detected GWEs marked as yellow. Regions marked as green indicates depolarizing half wave events that were not classified as engaging in a GWE. (C) Upper panel. Voltage trace (raw signal in gray, high pass (>0.5 Hz) filtered in black), averaged across both hemispheres. Lower panel. Fraction of pixels of both hemispheres exhibiting depolarizing half waves. Gray shaded epochs indicate times of individual GWEs. Example data are from animal #6.