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Time course of the mean change from baseline profile in least squares means for the pain tolerance threshold for (A,B) pressure stimulation, (C,D) the heat pain detection threshold for thermal testing on normal skin, and (E,F) UVB‐irradiated skin and (G,H) the thermal grill maximum unpleasantness VAS after administration of the different compounds in (A,C,E,G) part I and (B,D,F,H) part II
