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. 2016 Dec 14;312(3):R292–R300. doi: 10.1152/ajpregu.00401.2016

Fig. 2.

Fig. 2.

Effect of CGP52432 (intravenous) on the inhibition of bladder overactivity induced by tibial nerve stimulation (TNS) in female cats. A: repeated CMGs at different cumulative doses of CGP52432 were performed during acetic acid (AA) infusion with or without TNS. Black bars under the pressure trace indicate TNS duration. TNS: 5 Hz, 0.2 ms, T = 3 V. Infusion rate = 2 ml/min. B: normalized bladder capacity measured under different conditions (n = 5 cats). *Significantly (P < 0.05, Bonferroni comparisons) different from control at different dosages of CGP52432 (two-way ANOVA). #Significantly (P < 0.05, Bonferroni comparisons) different from the bladder capacity measured during TNS before CGP52432 treatment (one-way ANOVA).